First De Novo Synthesis of the Bisindole Alkaloid Vinblastine
✍ Scribed by Christoph Schneider
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 77 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0044-8249
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## Abstract Diazine‐bridged bisindoles are readily obtained from __N__‐Boc‐protected 3‐iodoindoles and 3‐iodo‐7‐azaindole in a pseudo three‐component reaction involving a one‐pot Masuda borylation–Suzuki arylation sequence. Some of the title compounds display promising cytotoxic properties. The ver