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Fertility in patients with 5-alpha-reductase-2 deficiency

✍ Scribed by Eunice Marumudi; Ariachery C. Ammini


Book ID
116478660
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
41 KB
Volume
95
Category
Article
ISSN
1556-5653

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Male pseudohermaphroditism caused by steroid 5␣-reductase deficiency is an autosomal recessive disorder. The enzyme steroid 5␣-reductase 2 (encoded by the SRD5A2 gene) catalyses the conversion of testosterone to dihydrotestosterone, which is required for normal differentiation of the external male g