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Giant Seminoma in a Patient With 5α-Reductase Type 2 Deficiency

✍ Scribed by SASAKI, GORO; NAKAGAWA, KEN; HASHIGUCHI, AKINORI; HASEGAWA, TOMONOBU; OGATA, TSUTOMU; MURAI, MASARU

Book ID
122948167
Publisher
Lippincott Williams and Wilkins
Year
2003
Tongue
English
Weight
316 KB
Volume
169
Category
Article
ISSN
0022-5347

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Male pseudohermaphroditism caused by steroid 5␣-reductase deficiency is an autosomal recessive disorder. The enzyme steroid 5␣-reductase 2 (encoded by the SRD5A2 gene) catalyses the conversion of testosterone to dihydrotestosterone, which is required for normal differentiation of the external male g