Familial polyposis coli and neurofibromatosis in the same patient: A family study
โ Scribed by Henry T. Lynch; Robert J. Fitzgibbons Jr.; Stephen J. Lanspa; Joseph N. Marcus; Jane F. Lynch; Levy Kopelovich
- Book ID
- 119103578
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 477 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0165-4608
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## Abstract Three cases of familial polyposis coli with adenomatous polyps of the upper gastro-intestinal tract are reported. This association has not previously been described in Britain, probably because no special attempt has been made to detect polyps in these situations. A careful study of kn
## Abstract Characteristic radio-opaque lesions were detected in the mandibular bone, most clearly on the panoramic X-ray, in 27 or 93ยท2 per cent out of 29 cases in 15 families with familial polyposis coli, including 21 cases without Gardner's stigmata, 7 cases with the incomplete syndrome and 1 wi
## Germline mutations within the adenomatous polyposis coli (APC ) gene, a tumor suppressor gene, are responsible for most cases of familial adenomatous polyposis (FAP), an autosomal dominantly inherited predisposition to colorectal cancer. To date, more than 300 germ-line causative mutations with