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Desmoid tumours in patients with familial adenomatous polyposis and desmoid region adenomatous polyposis coli mutations

✍ Scribed by D. Speake; D. G. Evans; F. Lalloo; N. A. Scott; J. Hill


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
101 KB
Volume
94
Category
Article
ISSN
0007-1323

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Familial adenomatous polyposis coli: Fiv
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## Germline mutations within the adenomatous polyposis coli (APC ) gene, a tumor suppressor gene, are responsible for most cases of familial adenomatous polyposis (FAP), an autosomal dominantly inherited predisposition to colorectal cancer. To date, more than 300 germ-line causative mutations with