reported an excess of maternal transmission in bipolar affective disorder in multiply affected families. In a sample of 130 families ascertained through a bipolar proband without regard to psychiatric family history we analysed the frequency of maternal (MAT) and paternal (PAT) transmissions, the mo
Familial analysis of bipolar affective disorder using logistic models
β Scribed by Dr. John Blangero; Robert C. Elston
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 329 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0741-0395
No coin nor oath required. For personal study only.
β¦ Synopsis
Data on bipolar affective disorder in 187 pedigrees from the Collaborative Depression Study were analyzed using logistic models that have been extended to incorporate age of onset information. Logistic regression analysis and segregation analysis revealed evidence for complex familial effects on this disorder.
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