Facile synthesis of two pyridine alkaloids via functionalized 3,4-dialkylpyridines
β Scribed by Shiao, Min Jen; Chia, Win Long; Peng, Chin Jen; Shen, Chien Chang
- Book ID
- 111923112
- Publisher
- American Chemical Society
- Year
- 1993
- Tongue
- English
- Weight
- 423 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0022-3263
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## Abstract For Abstract see ChemInform Abstract in Full Text.
A facile, solvent free, ecofriendly approach for the synthesis of 2-amino-3(ethylcarboxy)-4,6-disubstituted pyridine 4 and pyrazolo [3,4-b]pyridines 6 is herein described employing neat reaction conditions under microwave irradiation. This solventless methodology is environmentally benign as it comp
An efficient procedure for preparation of the simple alkaloids, 2,3-polymethylene-4(3H)-quinazolinones, luotonin A, tryptanthrin, and rutaecarpine has been established by the reaction of lactam-HCl salts with POCl 3 followed by cyclization with methyl anthranilate.