A Facile Synthesis of 3-(2-Amino-4-ethoxyphenyl)pyridine
โ Scribed by Ohta, Tomio; Shibuya, Kimiyuki; Shigyo, Hiromichi
- Book ID
- 111877341
- Publisher
- Japan Institute of Heterocyclic Chemistry
- Year
- 1990
- Tongue
- English
- Weight
- 152 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0385-5414
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## Abstract For Abstract see ChemInform Abstract in Full Text.
A facile, solvent free, ecofriendly approach for the synthesis of 2-amino-3(ethylcarboxy)-4,6-disubstituted pyridine 4 and pyrazolo [3,4-b]pyridines 6 is herein described employing neat reaction conditions under microwave irradiation. This solventless methodology is environmentally benign as it comp
In a three-step sequence starting from readily available starting materials, 2,3-carbon disubstituted furo[2,3-b]pyridines can be accessed in good yields and purity. Furo[2,3-b]pyridines bearing ester, amide and ketone groups at the 2-position can be prepared with a variety of aryl and alkyl groups