In the title compound, C 12 H 9 BrClN 3 O 3 , the nitro group lies in the plane of the imidazole ring, whereas the benzene and acetyl groups are markedly twisted relative to the heterocyclic ring. A weak C-HΓ Γ ΓO interaction helps to establish the crystal packing.
Facile synthesis of enantiomerically pure 1-(5-bromo-2-chlorophenyl)-1-(4-ethoxyphenyl)ethane
β Scribed by Zhang, Shuo; Wang, Wenjin; Li, Chuan; Liu, Peng; Xu, Weiren; Tang, Lida; Wang, Jianwu; Zhao, Guilong
- Book ID
- 125386602
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 603 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1005-9040
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π SIMILAR VOLUMES
The title compound, C 15 H 7 BrCl 3 FO, crystallizes with two molecules in the asymmetric unit. The molecular conformation is stabilized by C-HΓ Γ ΓBr intramolecular interactions.
Addition of molecular fluorine to cis-2-cyclopentene-1 ,Cdiol gave the c&anti adduct stereoselectively. This meso diol was dissymmetrized by means of acetylation under lipase catalysis to afford the monoacetate with a high enatiomeric purity. Oxidation of the monoacetate followed by elimination of h