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A facile synthesis of 2,3-disubstituted furo[2,3-b]pyridines

✍ Scribed by Gregory L. Beutner; Jeffrey T. Kuethe; Nobuyoshi Yasuda

Publisher: Elsevier Science
Year: 2009
Tongue: French
Weight: 174 KB
Volume: 50
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2008.11.125

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✦ Synopsis

In a three-step sequence starting from readily available starting materials, 2,3-carbon disubstituted furo[2,3-b]pyridines can be accessed in good yields and purity. Furo[2,3-b]pyridines bearing ester, amide and ketone groups at the 2-position can be prepared with a variety of aryl and alkyl groups at the 3position.

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