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Facile Synthesis of Imidazo[1,2-a]pyridines via Tandem Reaction

✍ Scribed by Wang, Jian-Wu; Tao, Xu-Tang; Jia, Jiong; Ge, Yan-Qing

Book ID
120077674
Publisher
Japan Institute of Heterocyclic Chemistry
Year
2010
Tongue
English
Weight
699 KB
Volume
81
Category
Article
ISSN
0385-5414

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πŸ“œ SIMILAR VOLUMES

Solid-phase synthesis of imidazo[1,2-a]p
Solid-phase synthesis of imidazo[1,2-a]pyridines and imidazo[1,2-a]pyrimidines
✍ Saı̈d El Kazzouli; Sabine Berteina-Raboin; Abderrahim Mouaddib; GΓ©rald Guillaume πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 409 KB

The synthesis of imidazo [1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives by condensation between an a-bromoketone bound to solid support and various 2-aminopyridine or 2-aminopyrimidine derivatives was described. Either an acid labile linker or a base labile linker was used in this study.

Synthesis of imidazo[1,2a]pyridines via
Synthesis of imidazo[1,2a]pyridines via three-component reaction of 2-aminopyridines, aldehydes and alkynes
✍ Ping Liu; Li-song Fang; Xinsheng Lei; Guo-qiang Lin πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 French βš– 333 KB

A novel three-component reaction towards the synthesis of imidazo [1,2a]pyridines was independently developed based on 2-aminopyridines, aldehydes and alkynes, and thereby imidazo[1,2a]pyridines were obtained in acceptable yields by the CuSO4/TsOH catalyzed three-component reaction.