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Synthesis of imidazo[1,2a]pyridines via three-component reaction of 2-aminopyridines, aldehydes and alkynes

✍ Scribed by Ping Liu; Li-song Fang; Xinsheng Lei; Guo-qiang Lin

Publisher: Elsevier Science
Year: 2010
Tongue: French
Weight: 333 KB
Volume: 51
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2010.05.139

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✦ Synopsis

A novel three-component reaction towards the synthesis of imidazo [1,2a]pyridines was independently developed based on 2-aminopyridines, aldehydes and alkynes, and thereby imidazo[1,2a]pyridines were obtained in acceptable yields by the CuSO4/TsOH catalyzed three-component reaction.

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