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Facile synthesis of functionalized 4-aminopyridines

โœ Scribed by Nishiwaki, Nagatoshi; Azuma, Mayumi; Tamura, Mina; Hori, Kazushige; Tohda, Yasuo; Ariga, Masahiro


Book ID
120372578
Publisher
Royal Society of Chemistry
Year
2002
Tongue
English
Weight
102 KB
Volume
18
Category
Article
ISSN
1359-7345

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A facile synthesis of functionalized cat
โœ Chaozhong Li; Robert J. angelici ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 191 KB

A general route to functionalized catechols is achieved by the reaction of 3,6-di(chloromethyl)-4,5dimethyl-catechol with various nucleophiles in the presence of a base. The reactions are proposed to occur by way of a dehydrochlorinated intermediate which undergoes Michael additions to give the cate