Synthesis of N1β²-([11C]methyl)naltrindol
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John R. Lever; Chris M. Kinter; Hayden T. Ravert; John L. Musachio; William B. M
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Article
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1995
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John Wiley and Sons
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French
β 508 KB
## Abstract A delta opioid receptor antagonist, N1β²βmethylnaltrindole (MeNTI), has been labeled with carbonβ11. The precursor for radiolabeling was prepared in 71% yield by benzylation of the phenolic moiety of naltrindole. Alkylation of the indole nitrogen using [^11^C]iodomethane and aqueous tetr