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Extramedullary relapse in acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy

✍ Scribed by de Botton, S; Sanz, M A; Chevret, S; Dombret, H; Martin, G; Thomas, X; Mediavilla, J D; Recher, C; Ades, L; Quesnel, B

Book ID
110056527
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
183 KB
Volume
20
Category
Article
ISSN
0887-6924

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## Abstract ## Background Due to severe side effects in virtually all children treated with a standard dose of 45 mg/m^2^/day all‐__trans__‐retinoic acid (ATRA) for acute promyelocytic leukemia (APL) the AML‐BFM study group reduced the dosage to 25 mg/m^2^/day. For the lack of data on the use of A