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Central nervous system relapse in acute promyelocytic leukaemia treated with all-trans retinoic acid

✍ Scribed by Seldon, M. ;Enno, A.


Book ID
108999925
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
90 KB
Volume
28
Category
Article
ISSN
0004-8291

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Pharmacology of all-trans-retinoic acid
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## Abstract ## Background Due to severe side effects in virtually all children treated with a standard dose of 45 mg/m^2^/day all‐__trans__‐retinoic acid (ATRA) for acute promyelocytic leukemia (APL) the AML‐BFM study group reduced the dosage to 25 mg/m^2^/day. For the lack of data on the use of A