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Effect of all-trans-retinoic acid alone or in combination with chemotherapy in newly diagnosed acute promyelocytic leukaemia

✍ Scribed by Milica D. Čolović; Gradimir M. Janković; Ivo Elezović; Ana Vidović; Jelena S. Bila; Angelina Novak; Dragan Babić


Publisher
Springer US
Year
1997
Tongue
English
Weight
921 KB
Volume
14
Category
Article
ISSN
1357-0560

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## Abstract ## Background Due to severe side effects in virtually all children treated with a standard dose of 45 mg/m^2^/day all‐__trans__‐retinoic acid (ATRA) for acute promyelocytic leukemia (APL) the AML‐BFM study group reduced the dosage to 25 mg/m^2^/day. For the lack of data on the use of A