## Response to "Treatment of Childhood Chronic ITP" Prompted by recent correspondence in the Journal (July 1994), may I contribute the experience from this center in the use of megadose prednisone for chronic immune thrombocytopenic purpura (ITP) in children? A cohort of 4 children received this
Successful treatment of acute promyelocytic leukemia in pregnancy with all-trans retinoic acid
β Scribed by K. Nakamura; K. Dan; R. Iwakiri; S. Gomi; T. Nomura
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 133 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0939-5555
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π SIMILAR VOLUMES
Acute promyelocytic leukemia is characterized by the reciprocal translocation of chromosomes 15 and 17. All-trans retinoic acid (ATRA) efficiently induces differentiation of the abnormal promyelocytes. In this study, we had used ATRA as the primary induction therapy for 17 newly diagnosed patients,
## Abstract ## Background Due to severe side effects in virtually all children treated with a standard dose of 45 mg/m^2^/day allβ__trans__βretinoic acid (ATRA) for acute promyelocytic leukemia (APL) the AMLβBFM study group reduced the dosage to 25 mg/m^2^/day. For the lack of data on the use of A