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Expression of Tel-Aml1 transcript variants in pediatric acute lymphoblastic leukemia

✍ Scribed by Kustanovich, A M; Belevtsev, M V; Stasevich, I V; Savitskaya, T V; Jutzkevich, R I; Savva, N N; Aleinikova, O V

Book ID: 110056549
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 115 KB
Volume: 20
Category: Article
ISSN: 0887-6924
DOI: 10.1038/sj.leu.2404028

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Acute lymphoblastic leukemia (ALL) is the most common form of childhood cancer. The peak incidence of ALL between ages 2 and 5 is accounted for by one subtype, referred to as common acute lymphoblastic leukemia (cALL). About 25% of cALL patients have the TEL-AML1 gene fusion derived from the t(12;21