Expression of decorin and collagens I and III in different layers of human skin in vivo: a laser capture microdissection study
✍ Scribed by Katrin Lochner; Astrid Gaemlich; Kirstin Marie Südel; Kirsten Venzke; Ingrid Moll; Anja Knott; Franz Stäb; Horst Wenck; Olaf Döring; Michael Böttger; Stefan Gallinat
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 282 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1389-5729
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In vitro human skin fibroblasts aging was characterized by a continuous increase of collagenase mRNA levels. On the contrary, TIMP‐1 mRNA level decreased only at late passages (> 65% of proliferative life span). Type I and III mRNA levels showed a high variability depending on cell strains studied.