๐”– Bobbio Scriptorium
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Exogenous spermine reduces ischemic damage in a model of focal cerebral ischemia in the rat

โœ Scribed by Bert A Coert; Robert E Anderson; Fredric B Meyer

Book ID
117470528
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
426 KB
Volume
282
Category
Article
ISSN
0304-3940

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## Abstract The proinflammatory cytokine interleukinโ€1 (ILโ€1) is a key mediator of inflammation in cerebral ischemia, but its precise mechanisms of action remain elusive. Temperature is critical to outcome in brain injury and given the importance of ILโ€1 in pyrogenesis this has clear mechanistic im