Anti-CD11b monoclonal antibody reduces ischemic cell damage after transient focal cerebral ischemia in rat

Steady plasma concentration of unfractio

Steady plasma concentration of unfractionated heparin reduces infarct volume and prevents inflammatory damage after transient focal cerebral ischemia in the rat

✍ Álvaro Cervera; Carles Justicia; Joan C. Reverter; Anna M. Planas; Ángel Chamorr 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 178 KB

## Abstract Unfractionated heparin (UH) decreases the extent of infarction after transient focal brain ischemia in the rat and abridges neuroinflammatory damage in patients with acute stroke. This study was aimed at assessing whether controlled and steady heparinemia in plasma can reduce infarct vo