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Ischemic post-conditioning protects brain and reduces inflammation in a rat model of focal cerebral ischemia/reperfusion

✍ Scribed by Bianzhi Xing; Hui Chen; Min Zhang; Dongming Zhao; Rui Jiang; Xiuheng Liu; Suming Zhang


Book ID
111180780
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
437 KB
Volume
105
Category
Article
ISSN
0022-3042

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## Abstract The proinflammatory cytokine interleukin‐1 (IL‐1) is a key mediator of inflammation in cerebral ischemia, but its precise mechanisms of action remain elusive. Temperature is critical to outcome in brain injury and given the importance of IL‐1 in pyrogenesis this has clear mechanistic im