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Evidence for the involvement of a tyrosine kinase activity in thapsigargin-dependent contractions of pulmonary vascular smooth muscle

✍ Scribed by P. Gonzalez De La Fuente; R. Marthan; J.P. Savineau

Book ID
119180135
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
173 KB
Volume
31
Category
Article
ISSN
1043-6618

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πŸ“œ SIMILAR VOLUMES

Effect of Modulators of Tyrosine Kinase
Effect of Modulators of Tyrosine Kinase Activity on Agonist-induced Contraction in the Rat Pulmonary Vascular Smooth Muscle
✍ J.P. Savineau; P. Gonzalez De La Fuente; R. Marthan πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier 🌐 English βš– 155 KB

In the rat isolated main pulmonary artery, we investigated the effect of a tyrosine kinase inhibitor (genistein) and that of a tyrosine phosphatase inhibitor (phenylarsine oxide) on agonist-induced contraction. Genistein (10 microM) reduced the amplitude of the contraction evoked by noradrenaline (0