Evidence for the Involvement of a Src-Related Tyrosine Kinase inXenopusEgg Activation
β Scribed by Ken-ichi Sato; Yasuhiro Iwao; Tomoko Fujimura; Ikuo Tamaki; Keiko Ogawa; Tetsushi Iwasaki; Alexander A Tokmakov; Osamu Hatano; Yasuo Fukami
- Book ID
- 115598080
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 412 KB
- Volume
- 209
- Category
- Article
- ISSN
- 0012-1606
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## Abstract The discoidin domain receptor 1 (DDR1) is a receptor tyrosine kinase that is highly expressed in breast carcinoma cells. Upon binding to collagen, DDR1 undergoes autophosphorylation followed by limited proteolysis to generate a tyrosine phosphorylated Cβterminal fragment (CTF). Although