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Effect of vascular smooth muscle relaxants on the protein kinase C-mediated contraction in the rat pulmonary artery

โœ Scribed by Jean-Pierre Savineau; Patrick Gonzalez De La Fuente; Roger Marthan

Book ID
115888545
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
773 KB
Volume
249
Category
Article
ISSN
0014-2999

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๐Ÿ“œ SIMILAR VOLUMES

Effect of Modulators of Tyrosine Kinase
Effect of Modulators of Tyrosine Kinase Activity on Agonist-induced Contraction in the Rat Pulmonary Vascular Smooth Muscle
โœ J.P. Savineau; P. Gonzalez De La Fuente; R. Marthan ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier ๐ŸŒ English โš– 155 KB

In the rat isolated main pulmonary artery, we investigated the effect of a tyrosine kinase inhibitor (genistein) and that of a tyrosine phosphatase inhibitor (phenylarsine oxide) on agonist-induced contraction. Genistein (10 microM) reduced the amplitude of the contraction evoked by noradrenaline (0