Evaluation of the metabolism and hepatotoxicity of styrene in F344 rats, B6C3F1 mice, and CD-1 mice following single and repeated inhalation exposures
โ Scribed by Susan C.J Sumner; Russell C Cattley; Bahman Asgharian; Derek B Janszen; Timothy R Fennell
- Book ID
- 114009453
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 533 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0009-2797
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๐ SIMILAR VOLUMES
Glycidol, a simple aliphatic epoxide, was administered by gavage in water to groups of male and female F344/N rats and B6C3F1 mice. Rats received 0, 37.5 or 75 mg kg-' and mice received 0, 25 or 50 mg kg-' daily, 5 days per week for 2 years. Exposure to glycidol was associated with dose-related incr
Groups of F344 rats and B6C3F 1 mice were exposed to furfuryl alcohol vapor for 6 hours per day, 5 days per week for 14 days (0, 16, 31, 63, 125, 250 ppm) or 13 weeks (0, 2, 4, 8, 16, 32 ppm). Reduced survival was observed in the 14-day study at 250 ppm. Final mean body weights of rats and mice expo