Comparison of Styrene Hepatotoxicity in B6C3F1 and Swiss Mice
โ Scribed by Daniel L. Morgan; Joel F. Mahler; Michael P. Moorman; Ralph E. Wilson; Herman C. Price Jr.; Judy H. Richards; Robert W. O'Connor
- Book ID
- 115608507
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 306 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0272-0590
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## Abstract The oral and i.v. elimination kinetics were investigated for bromodichloroacetate (BDCA), a haloacetate found in drinking water. The BDCA was administered at a dose of 5, 20 and 100 mg kg^โ1^ to B6C3F1 mice and appears to distribute to the total body water with a mean volume of distribu
Butadiene and styrene are oxidized, in part, by eral blood. Butadiene and mixtures of butadiene cytochrome P450 2E1 and have been shown to and styrene were genotoxic in mice, as shown by metabolically interact in rodents exposed by inhala-a significant increase in the frequency of micronution to mix