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Sensory irritation structure-activity study of inhaled aldehydes in B6C3F1 and Swiss-Webster mice

✍ Scribed by W.H. Steinhagen; C.S. Barrow

Book ID
113206289
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
772 KB
Volume
72
Category
Article
ISSN
0041-008X

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The expiratory bradypnea indicative of upper airway irritation in mice was evaluated during a 15-min oronasal exposure to increasing concentrations of sixteen aliphatic amines. The airborne concentration resulting in a 50% decrease in the respiratory rate of mice ( R D ~~) was calculated for each te