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Evaluation of impurities in simvastatin drug products with the use of FT-IR spectroscopy and selected chemometric techniques

✍ Scribed by Kupcewicz, Bogumiła ;Ronowicz, Joanna ;Balcerowska-Czerniak, Grażyna ;Walasek, Andrzej ;Budzisz, Elżbieta


Book ID
120839157
Publisher
Walter de Gruyter GmbH
Year
2013
Tongue
English
Weight
977 KB
Volume
11
Category
Article
ISSN
2391-5420

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Evaluation of impurities in simvastatin
✍ Kupcewicz, Bogumiła ;Ronowicz, Joanna ;Balcerowska-Czerniak, Grażyna ;Walasek, A 📂 Article 📅 2013 🏛 Walter de Gruyter GmbH 🌐 English ⚖ 977 KB

## Abstract In the present study a reversed phase high performance liquid chromatography (RP-HPLC) method with diode array detector (DAD) at room temperature was used for obtaining impurity profiles of 20 drug products containing simvastatin as an active substance. Fourier-transform infrared spectr