๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Evaluation of 5-aminosalicyltaurine as a colon-specific prodrug of 5-aminosalicylic acid for treatment of experimental colitis

โœ Scribed by Yunjin Jung; Hak-Hyun Kim; Heejung Kim; Hyesik Kong; Boim Choi; Youngwook Yang; Youngmi Kim


Book ID
113591605
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
326 KB
Volume
28
Category
Article
ISSN
0928-0987

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


N,Nโ€ฒ-Bis(5-aminosalicyl)-L-cystine is a
โœ Heejung Kim; Jeongsoon Huh; Hyunchu Jeon; Daekyu Choi; Jungoh Han; Youngmi Kim; ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 215 KB

To evaluate N,N 0 -bis(5-aminosalicyl)-L-cystine (5-ASA-Cys) as a potential colon-specific 5-aminosalicylic acid prodrug with dual therapeutic effects in experimental colitis, the pharmacokinetics and therapeutic activity were investigated after oral administration of 5-ASA-Cys and amelioration of e

Colon-specific prodrugs of 5-aminosalicy
โœ Yun Jin Jung; Jeoung Soo Lee; Young Mi Kim ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 159 KB ๐Ÿ‘ 1 views

5-Aminosalicyl-L-aspartic acid (5-ASA-Asp) and 5-aminosalicyl-L-glutamic acid (5-ASA-Glu) were synthesized and their properties as colon-speciยฎc prodrugs of 5aminosalicylic acid (5-ASA) were investigated employing rats as test animals. Incubation of 5-ASA-Asp and 5-ASA-Glu with the homogenates of ti