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Evaluating the role(s) of Lrp5/6 and WNT ligands in regulating bone development and acquisition

✍ Scribed by B.O. Williams

Book ID
116324196
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
71 KB
Volume
48
Category
Article
ISSN
8756-3282

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## Abstract LDL‐receptor related proteins 5 and 6 (LRP5/6) are co‐receptors of Frizzled receptors that mediate Wnt‐induced activation of the transcription factor family TCF/LEF‐1. Even though LRP5 and LRP6 are highly homologous, LRP6, but not LRP5, is expressed primarily in the nervous system and d