The role of hox genes in limb development and bone formation
β Scribed by S. Mundlos
- Book ID
- 116324173
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 53 KB
- Volume
- 48
- Category
- Article
- ISSN
- 8756-3282
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During vertebrate limb development, various genes of the Hox family, the products of which influence skeletal element identity, are expressed in specific spatiotemporal patterns in the limb bud mesenchyme. At the same time, the cells also exhibit 'self-organizing' behavior -interacting with each oth
## Abstract The __HOMβC__ clustered prototype homeobox genes of __Drosophila__, and their counterparts, the __HOX__ genes in humans, are highly conserved at the genomic level. These master regulators of development continue to be expressed throughout adulthood in various tissues and organs. The phy