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Goosecoid misexpression alters the morphology and Hox gene expression of the developing chick limb bud

✍ Scribed by Tiffany A Heanue; Randy L Johnson; Juan-Carlos Izpisua-Belmonte; Claudio D Stern; Eddy M De Robertis; Clifford J Tabin


Book ID
118603024
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
545 KB
Volume
69
Category
Article
ISSN
0925-4773

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Several polydactylous mutants affect the pattern of asymmetry along the anteroposterior axis of the vertebrate limb. In talpid,, diplopodia,, and diplopodia, chick limb mutants, there is a preaxial extension that results in broader limb buds. Talpid, shows reduction of the long bones and 9-1 0 synda