Role of the intracellular domains of LRP
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Kaihong Mi; Gail V.W. Johnson
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Article
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2005
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John Wiley and Sons
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English
β 295 KB
π 2 views
## Abstract LDLβreceptor related proteins 5 and 6 (LRP5/6) are coβreceptors of Frizzled receptors that mediate Wntβinduced activation of the transcription factor family TCF/LEFβ1. Even though LRP5 and LRP6 are highly homologous, LRP6, but not LRP5, is expressed primarily in the nervous system and d