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Ethyl chlorocarbonate-14C and its application to the synthesis of N-methyl-14C-amines

✍ Scribed by F. J. Marshall; R. E. McMahon

Publisher
John Wiley and Sons
Year
1970
Tongue
French
Weight
262 KB
Volume
6
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

A convenient method for the preparation of ethyl chlorocarbonate‐^14^C is described. This has led to a facile synthesis of N‐methyl‐^14^C secondary amines by lithium aluminum hydride reduction of an intermediate ^14^C‐carbamate. The reaction has also been employed in the preparation of N‐methyl‐^2^H~3~‐ and N‐methyl‐^3^ H‐amines by using lithium aluminum hydride‐^2^ H~4~and lithium aluminum hydride‐^3^H.

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