Ethyl (2R,3R,SR)-3-(ethoxycarbonyloxy)-2-[1-(p-tolylsulfinyl)cyclopropyl]-1-pyrrolidinecarboxylate
โ Scribed by Robinson, P. D. ;Hua, D. H. ;Wu, X. ;Miao, S. W. ;Meled, M.
- Book ID
- 114509719
- Publisher
- International Union of Crystallography
- Year
- 1992
- Tongue
- English
- Weight
- 337 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0108-2701
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๐ SIMILAR VOLUMES
A convenient, efficient and cost-effective two-stage synthesis of benzyl (3R)-3-amino-2-oxo-1-pyrrolidinecarboxylate (2S,3S)-2,3-bis[(4-methylbenzoyl)oxy]butanediote (2:1) via a crystallisation-induced dynamic resolution process is reported.
The relative conยฎguration of the title compound, C 18 H 27 NO 4 , was determined as being R,S,S,S. There are three crystallographically independent molecules in the asymmetric unit, which show only slight conformational differences. Molecules in the crystal structure are connected by hydrogen bonds