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Ethanol decreases agrin-induced acetylcholine receptor clustering in C2C12 myotube culture

✍ Scribed by David B. Owen; Kevin T. Chamberlain; Sonia Shishido; Wade A. Grow

Book ID
116920140
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
419 KB
Volume
24
Category
Article
ISSN
0887-2333

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## Abstract Protein kinase C (PKC) activity has been implicated in nicotinic acetylcholine receptor (nAChR) cluster disruption but the specific PKC isoforms involved have not been identified. We first tested whether phorbol esters, which activate PKCs, regulate agrin‐induced nAChR clustering in C~2