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Estimation of theophylline absorption rate by means of the Wagner-Nelson equation

✍ Scribed by WAGNER, J


Book ID
119058042
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
567 KB
Volume
78
Category
Article
ISSN
1097-6825

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t in pharmacokinetics the Wagner-Nelson method is oftcn ,.:':,,~ti for cstiwating the absorption rate of a drug in different situations. The program described here a~plic, ibis method to a cnc-o,mpartment model for pla,,,ma drug concentrations an,; comes with several graphs, statistical tests and el

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Some authors have used an elimination rate constant derived from one theophylline treatment (e.g. the elixir) to apply the Wagner-Nelson method to concentration-time data from another treatment (e.g. a sustained-release form). Since there is considerable intrasubject variation in the elimination rat