Having obtained the amino acid composition of a protein, chemists and molecular biologists may wish to identify the protein from this data alone. In general such data will have errors associated with them and the length of the protein may be known only approximately or not at all. In this paper a me
Estimation of primary sequence homology from amino acid composition of evolutionary related proteins
β Scribed by Curtis E. Harris; David C. Teller
- Publisher
- Elsevier Science
- Year
- 1973
- Tongue
- English
- Weight
- 915 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0022-5193
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The multidimensional statistical technique of discriminant analysis is used to allocate amino acid sequences to one of four secondary structural classes: high a content, high / 3 content, mixed a and @, low content of ordered structure. Discrimination is based on four attributes: estimates of percen
In proteins, immunogenic determinants that can induce protein-reactive antipeptide antibodies reside mostly in those parts of the molecule that have a high tendency to form &turns. A program for an IBM personal computer which predicts protein immunogenic determinants is described. The program predic