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Epigenetic Silencing of EcSOD Promotes the Invasive Phenotype in Human Lung Cancer

✍ Scribed by Matthew P. Fitzgerald; Lai Tee Teoh-Fitzgerald; Taylor J. Jensen; Frederick E. Domann

Book ID
113631309
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
386 KB
Volume
49
Category
Article
ISSN
0891-5849

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## Abstract The serine protease family member __PRSS3__ (__trypsinogen‐IV__) has been implicated as a putative tumor suppressor gene due to its loss of expression, which is correlated with promoter hypermethylation, in esophageal squamous cell carcinoma and gastric adenocarcinoma. As epigenetic alt