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Epigenetic silencing of human T (brachyury homologue) gene in non-small-cell lung cancer

✍ Scribed by Jong Chul Park; Young Kwang Chae; Choon Hee Son; Myoung Sook Kim; Juna Lee; Kimberly Ostrow; David Sidransky; Mohammad Obaidul Hoque; Chulso Moon


Book ID
116295895
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
581 KB
Volume
365
Category
Article
ISSN
0006-291X

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## Abstract The serine protease family member __PRSS3__ (__trypsinogen‐IV__) has been implicated as a putative tumor suppressor gene due to its loss of expression, which is correlated with promoter hypermethylation, in esophageal squamous cell carcinoma and gastric adenocarcinoma. As epigenetic alt