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Frequent Epigenetic Silencing of thep16Gene in Non-small Cell Lung Cancers of Tobacco Smokers

✍ Scribed by Yanagawa, Naoki ;Tamura, Gen ;Oizumi, Hiroyuki ;Takahashi, Nobumasa ;Shimazaki, Yasuhisa ;Motoyama, Teiichi


Book ID
108582094
Publisher
Wiley (Blackwell Publishing)
Year
2002
Tongue
English
Weight
508 KB
Volume
93
Category
Article
ISSN
0910-5050

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## Abstract The serine protease family member __PRSS3__ (__trypsinogen‐IV__) has been implicated as a putative tumor suppressor gene due to its loss of expression, which is correlated with promoter hypermethylation, in esophageal squamous cell carcinoma and gastric adenocarcinoma. As epigenetic alt