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Epidermal growth factor stimulates phosphatidylinositol turnover for ten hours in A431 cells without activation of protein kinase C

✍ Scribed by David M. Thompson; Jim Proctor; Michael Grant; Craig Thomas

Book ID
117058129
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
279 KB
Volume
155
Category
Article
ISSN
0006-291X

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## Abstract Epidermal growth factor (EGF), which stimulates tyrosine‐specific protein kinase activity both in vivo and in vitro, inhibits proliferation of A431 human epidermoid carcinoma cells. After mutagenesis clonal cell lines that were resistant to the growth inhibitory effects of EGF were sele