✦ LIBER ✦

Epidermal growth factor stimulates phosphatidylinositol turnover in human foreskin fibroblasts without activation of protein kinase C

✍ Scribed by David M. Thompson; Craig Thomas; Grant Kinsey

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 315 KB
Volume: 41
Category: Article
ISSN: 0730-2312
DOI: 10.1002/jcb.240410405

No coin nor oath required. For personal study only.

✦ Synopsis

Epidermal growth factor stimulates phosphatidylinositol turnover in human foreskin fibroblasts. This is a primary cell culture with normal numbers of epidermal growth factor receptors that is stimulated to divide by epidermal growth factor. Increases are seen in the inositol phospholipids and inositol phosphates. Despite this activation of phosphatidylinositol turnover, there is no detectable activation of protein kinase C.

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