Regulation of p42 Mitogen-Activated-Protein Kinase Activity by Protein Phosphatase 2A Under Conditions of Growth Inhibition by Epidermal Growth Factor in A431 Cells
β Scribed by Naima Chajry; Pierre-Marie Martin; Claude Cochet; Yolande Berthois
- Book ID
- 115131740
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 980 KB
- Volume
- 235
- Category
- Article
- ISSN
- 1432-1327
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## Abstract It is wellβknown that p38 mitogenβactivated protein kinase (p38MAPK) participates in cellular responses to mitogenic stimuli, environmental and genotoxic stresses, and apoptotic agents. Although there are several reports on p38MAPK in relation to cell growth and apoptosis, the exact mec
Compound 5 (Cpd 5), a synthetic K vitamin analogue, or 2-(2-mercaptoethanol)-3-methyl-1,4-naphthoquinone, is a potent inhibitor of epidermal growth factor (EGF)-induced rat hepatocyte DNA synthesis and induces EGF receptor (EGFR) tyrosine phosphorylation. To understand the cellular responses to Cpd