Regulation of protein breakdown by epidermal growth factor in A431 cells
β Scribed by F.J. Ballard
- Book ID
- 115891929
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 595 KB
- Volume
- 157
- Category
- Article
- ISSN
- 0014-4827
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## Abstract The metabolism of the receptor for epidermal growth factor (EGF) in Aβ431 cells has been measured by labeling the receptor in vivo with radioactive amino acid precursors and then determining, by immunoprecipitation with specific antiβEGF receptor antisera, the rate of degradation of the
## Abstract Epidermal growth factor (EGF), which stimulates tyrosineβspecific protein kinase activity both in vivo and in vitro, inhibits proliferation of A431 human epidermoid carcinoma cells. After mutagenesis clonal cell lines that were resistant to the growth inhibitory effects of EGF were sele