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Enhancement of recombinant erythropoietin production in CHO cells in an incubator without CO2addition

โœ Scribed by Sung Kwan Yoon; Yong-Ho Ahn; Kyuboem Han

Book ID
110391528
Publisher
Springer
Year
2001
Tongue
English
Weight
251 KB
Volume
37
Category
Article
ISSN
0920-9069

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Effect of culture temperature on erythro
Effect of culture temperature on erythropoietin production and glycosylation in a perfusion culture of recombinant CHO cells
โœ Woo Suk Ahn; Jae-Jin Jeon; Yeong-Ran Jeong; Seung Joo Lee; Sung Kwan Yoon ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 289 KB ๐Ÿ‘ 3 views

## Abstract To investigate the effect of culture temperature on erythropoietin (EPO) production and glycosylation in recombinant Chinese hamster ovary (CHO) cells, we cultivated CHO cells using a perfusion bioreactor. Cells were cultivated at 37ยฐC until viable cell concentration reached 1โ€‰ร—โ€‰10^7^ c