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In Vivo biological activities of recombinant human erythropoietin analogues produced by CHO cells, BHK cells and C127 cells

✍ Scribed by T. Hayakawa; M. Wada; K. Mizuno; S. Abe; M. Miyashita; M. Ueda


Book ID
114341253
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
376 KB
Volume
20
Category
Article
ISSN
1045-1056

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## Abstract Human recombinant erythropoietin (rHuEPO) was produced from Chinese hamster ovary (CHO) cells transfected with the human EPO gene. The cells were grown in batch cultures in controlled bioreactors in which the set‐points for dissolved oxygen varied between 3% and 200%. The cell‐specific