𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Epi-CHO, an episomal expression system for recombinant protein production in CHO cells

✍ Scribed by Rajkumar Kunaparaju; Mimi Liao; Noelle-Anne Sunstrom


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
237 KB
Volume
91
Category
Article
ISSN
0006-3592

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Regulation of XBP-1 signaling during tra
✍ Sebastian C. Y. Ku; Poh Choo Toh; Yih Yean Lee; Janet Chusainow; Miranda G. S. Y πŸ“‚ Article πŸ“… 2009 πŸ› American Institute of Chemical Engineers 🌐 English βš– 885 KB

## Abstract X‐box binding protein 1 (XBP‐1) is a key regulator of cellular unfolded protein response (UPR). The spliced isoform of XBP‐1, XBP‐1S, is a transcription activator, which is expressed only when UPR is induced. However, the impact of recombinant protein production on the regulation of XBP

Effect of doxycycline-regulated protein
✍ Chaya Mohan; Soon Hye Park; Joo Young Chung; Gyun Min Lee πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 133 KB πŸ‘ 2 views

## Abstract Protein disulfide isomerase (PDI), one of the ER‐resident molecular chaperones, forms and isomerizes disulfide bonds. This study attempts to investigate the effect of PDI expression level on specific productivity (__q__) of recombinant Chinese hamster ovary (rCHO) cells producing thromb

Identification of the limitations on rec
✍ Emma J. Mead; Lesley M. Chiverton; C. Mark Smales; Tobias von der Haar πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 234 KB πŸ‘ 2 views

## Abstract Mammalian cell lines are currently employed as one of the main cellular factories for the expression of recombinant protein‐based drugs. The establishment of high‐producing cell lines typically begins with a heterogeneous starter population of cells, from which the highest producing cel